Home > Books > DNA Polymerases: Discovery, Characterization and Functions in Cellular DNA Transactions
DNA Polymerases: Discovery, Characterization and Functions in Cellular DNA Transactions
View PDF

DNA Polymerases: Discovery, Characterization and Functions in Cellular DNA Transactions

Publication Year: 2010
Edition: 1st
Authors/Editor: Hübscher, Ulrich; Spadari, Silvio; Villani, Giuseppe; Maga, Giov
Publisher: World Scientific Publishing Co, Inc.
ISBN: 978-9-814-29916-9
  • Description
  • Details

This book summarizes the current knowledge of these fascinating enzymes. It is intended for a wide audience from basic scientists, to diagnostic laboratories and to clinicians who seek a better understanding of these fascinating enzymes.

Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics and in techniques to analyze ancient and otherwise damaged DNA. Moreover, some diseases are related to DNA polymerase defects, and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. We have recently witnessed the discovery of an abundance of novel DNA polymerases in viruses, bacteria, archaea and eukaryotes with specialized properties whose physiological functions are only beginning to be understood.

  • Platform:
    Ovid
  • Publisher: World Scientific Publishing Co, Inc.
  • Product Type: Book
  • Author/Editor: Hübscher, Ulrich; Spadari, Silvio; Villani, Giuseppe; Maga, Giov
  • ISBN: 978-9-814-29916-9
  • Specialty:
    Cell Biology
    Molecular Biology
  • Language: English
  • Edition: 1st
  • Pages: 340
  • Illustrations: 0
  • Year: 2010

Free Instant Access
This Month

JOTM
GIDEON: Global Infectious Diseases & Epidemiology Online Network Features up-to-date information and visual tools for diagnosing diseases and following the latest trends in epidemiology and treatment.
JOTM
Ovid Emcare A premium nursing and allied health database ideal for practice, research, or education.
JOTM
Journal of Hospital Medicine This journal is the premier publication for dissemination of research and education for the specialty of hospital medicine.
JOTM
Clinical Orthopaedics and Related Research® Original articles highlighting the latest in clinically relevant basic science of musculoskeletal diseases and their treatments.

Noteworthy

Doody's Featured Books
The Digital Echo Atlas: A Multimedia Reference
Provides expert clinical guidance and real-world cases throughout, ensuring that this resource is a go-to learning and reference tool useful for clinicians in the cardiology field.

Master Techniques in Orthopaedic Surgery: Relevant Surgical Exposures, 2nd Edition
Concise, lavishly illustrated reference designed to assist today’s orthopaedic surgeons in a crucial task: choosing and executing the exposure necessary for a given procedure.