Home > Books > Essentials of Pharmaceutical Preformulation
Essentials of Pharmaceutical Preformulation
View PDF

Essentials of Pharmaceutical Preformulation

Publication Year: 2012
Edition: 1st
Authors/Editor: Gaisford, Simon; Saunders, Mark
Publisher: Wiley
ISBN: 978-0-470-97635-7
  • Description
  • Details
  • Collections

A study guide which describes the basic principles of pharmaceutical physicochemical characterization.

Successful preformulation requires knowledge of fundamental molecular concepts (solubility, ionisation, partitioning, hygroscopicity and stability) and macroscopic properties (physical form, such as the crystalline and amorphous states, hydrates, solvates and co-crystals and powder properties), familiarity with the techniques used to measure them and appreciation of their effect on product performance, recognising that often there is a position of compromise to be reached between product stability and bioavailability.

This text introduces the basic concepts and discusses their wider implication for pharmaceutical development, with reference to many case examples of current drugs and drug products. Special attention is given to the principles and best-practice of the analytical techniques that underpin preformulation (UV spectrophotometry, TLC, DSC, XRPD and HPLC). The material is presented in the typical order that would be followed when developing a medicine and maps onto the indicative pharmacy syllabus of the Royal Pharmaceutical Society of Great Britain

  • Platform:
    Ovid
  • Publisher: Wiley
  • Product Type: Book
  • Author/Editor: Gaisford, Simon; Saunders, Mark
  • ISBN: 978-0-470-97635-7
  • Specialty:
    Pharmaceutical Science
    Pharmacology
  • Language: English
  • Edition: 1st
  • Pages: 268
  • Illustrations: 0
  • Year: 2012

Essentials of Pharmaceutical Preformulation is included in the following Collections:

Free Instant Access
This Month

JOTM
Social Policy & Practice A comprehensive bibliographic database, SSP helps professionals, practitioners, researchers, and students to understand, plan, and evaluate existing and future social policy.
JOTM
Visible Body Muscle Premium 3D interactive specialty module illustrates the basic movement of a variety of muscles throughout the human body as they interact with bone, nerves, and ligaments.
JOTM
Anesthesia & Analgesia Official journal of the International Anesthesia Research Society, provides the practice-oriented, clinical research to keep current and provide optimal care to patients.
JOTM
PAIN® Official publication of the International Association for the Study of Pain, publishes original research on the nature, mechanisms and treatment of pain.

Noteworthy

Doody's Featured Books
Harborview Illustrated Tips and Tricks in Fracture Surgery, 2nd Alumni Edition
Graduates of the Orthopaedic Trauma program at the University of Washington Harborview Medical Center provide tips and tricks gleaned from their years of professional practice.

Illustrated Tips and Tricks in Sports Medicine Surgery
Succinct, precise information from a wide range of experts and prestigious institutions on tackling technical problems in sports medicine surgery.