Home > Books > Preclinical Development Handbook: Toxicology
Preclinical Development Handbook: Toxicology
View PDF

Preclinical Development Handbook: Toxicology

Publication Year: 2008
Edition: 1st
Authors/Editor: Gad, Shayne Cox
Publisher: Wiley
ISBN: 978-0-470-24846-1
  • Description
  • Details

A clear, straightforward resource to guide you through preclinical drug development.

Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current methods and techniques.

Each chapter was written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.

Among the key topics covered are:
* In vitro mammalian cytogenetics tests
* Phototoxicity
* Carcinogenicity studies
* The pharmacogenomics of personalized medicine
* Bridging studies
* Toxicogenomics and toxicoproteomics

Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage.

This is a hands-on guide for pharmaceutical scientists involved in preclinical testing,enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.

  • Platform:
    Ovid
  • Publisher: Wiley
  • Product Type: Book
  • Author/Editor: Gad, Shayne Cox
  • ISBN: 978-0-470-24846-1
  • Specialty:
    Pharmacology
  • Language: English
  • Edition: 1st
  • Pages: 1080
  • Illustrations: 0
  • Year: 2008

Free Instant Access
This Month

JOTM
Ovid Emcare A premium nursing and allied health database ideal for practice, research, or education.
JOTM
PsycBOOKS® A database of peer-reviewed scholarly and professional books published by the American Psychological Association.
JOTM
Journal of Physical Therapy Education The premier forum for disseminating scholarly works in physical therapy educational theory and practice.
JOTM
Circulation Peer-reviewed reports on clinical and laboratory research relevant to cardiovascular disease.

Noteworthy

Doody's Featured Books
Greenfield's Surgery: Scientific Principles and Practice
The gold standard in the field of surgery, covers new technologies, innovative techniques, and integrating new scientific knowledge with evolving changes in surgical care.

Walsh & Hoyt's Clinical Neuro-Ophthalmology: The Essentials
Widely acknowledged as the definitive reference in the field, this title brings you the practical, hands-on information you need to effectively evaluate and manage neuro-ophthalmic conditions.