Home > Books > Septins, The
Septins, The
View PDF

Septins, The

Publication Year: 2008
Edition: 1st
Authors/Editor: Hall, Peter A.; Russell, S.E. Hilary; Pringle, John R.
Publisher: Wiley
ISBN: 978-0-470-51969-1
  • Description
  • Details

This book comprehensively examines the septin gene family and their proteins, providing those new to this research area with a detailed and wide-ranging introduction to septin biology.

Septins are an evolutionarily conserved group of GTP-binding and filament-forming proteins that were originally discovered in yeast. Once the preserve of a small band of yeast biologists, the field has grown rapidly in the past few years and now encompasses the whole of animal and fungal biology. Furthermore, septins are nowadays recognized to be involved in a variety of disease processes from neoplasia to neurodegenerative conditions.

The book starts with a unique historical perspective on the development of the field, from its beginnings in the screen for cell division mutants by the Nobel Laureate Lee Hartwell. The evolution of the septin gene family then forms a basis for consideration of the biochemistry and functions of septins in yeast and other model organisms including C. elegans and Drosophila.

A major part of the book considers the diversity of septins in mammals, their functions and properties as well as their involvement in normal and abnormal cellular states, followed by a speculative overview from the editors of the key questions in septin research and of where the field may be headed.

In addition, several appendices summarise important information for those in, or just entering, the field, e.g. nomenclature and septin and septin-like sequences.

This book is an essential source of reference material for researchers in septin biology, cell biology, genetics and medicine, in particular pathology, including areas of neurobiology, oncology, infectious disease and developmental biology.

  • Platform:
    Ovid
  • Publisher: Wiley
  • Product Type: Book
  • Author/Editor: Hall, Peter A.; Russell, S.E. Hilary; Pringle, John R.
  • ISBN: 978-0-470-51969-1
  • Specialty:
    Cell Biology
  • Language: English
  • Edition: 1st
  • Pages: 380
  • Illustrations: 0
  • Year: 2008

Free Instant Access
This Month

JOTM
Ovid Emcare A premium nursing and allied health database ideal for practice, research, or education.
JOTM
PsycBOOKS® A database of peer-reviewed scholarly and professional books published by the American Psychological Association.
JOTM
Journal of Physical Therapy Education The premier forum for disseminating scholarly works in physical therapy educational theory and practice.
JOTM
Circulation Peer-reviewed reports on clinical and laboratory research relevant to cardiovascular disease.

Noteworthy

Doody's Featured Books
Greenfield's Surgery: Scientific Principles and Practice
The gold standard in the field of surgery, covers new technologies, innovative techniques, and integrating new scientific knowledge with evolving changes in surgical care.

Walsh & Hoyt's Clinical Neuro-Ophthalmology: The Essentials
Widely acknowledged as the definitive reference in the field, this title brings you the practical, hands-on information you need to effectively evaluate and manage neuro-ophthalmic conditions.