SilverPlatter Guide


Drug Information Fulltext (DRUG)

Guide Index:
About Drug Information Fulltext (DRUG)
Combining Searches
Fields in Drug Information Fulltext (DRUG)
Classifications
Concept Codes, Alphabetical
Concept Codes, by Subject
Finding Word Variants
Stopwords
Table of Contents
Using Limit Fields
Search Examples

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About Drug Information Fulltext

Drug Information Fulltext (DRUG) is a full text database that combines the contents of two major publications. The Handbook on Injectable Drugs (HID) is the most trusted reference on stability and compatibility of injectable drug products. Included are monographs on more than 300 commercial drugs used in admixtures and important information on investigational drugs. The AHFS Drug Information is an unbiased, authoritative reference that provides evaluative information on virtually every single-drug entity available in the United States. Over 50,000 drug products are covered in detail, with information on drug uses (including unlabeled uses), cautions, interactions, chemistry and stability, pharmacology, pharmacokinetics, toxicity, dosage and administration, preparations, and more.

Copyright, Drug Information Fulltext, American Society of Hospital Pharmacists, Inc., 1993 to present. All rights reserved.

Copyrights of SilverPlatter International N.V.: Search and Retrieval Software, 1990 to present; guide files, indexes and supporting files, 1994 to present.

"SilverPlatter" is a registered trademark of SilverPlatter International N.V. The SilverPlatter logo, the quarter arc, "SilverLinker," "ERL," "ERL compliant," "SPIRS," "PC-SPIRS," "WinSPIRS," "WebSPIRS," "UNIX-SPIRS," "SPIRS Full-Text," "NEC SPIRS," and "MacSPIRS" are trademarks of SilverPlatter International N.V. The Subscriber may use Drug Information Fulltext for research purposes only, and may not publish, reproduce, transmit, store in any information retrieval system, or otherwise make available or sell the disc or its contents, whether in hard copy, electronically transmitted or any other form, and whether for commercial, educational or other purposes, other than for its own internal purposes or otherwise in accordance with the Subscription and License Agreement. American Society of Hospital Pharmacists, Inc. uses its best efforts to ensure that Drug Information Fulltext contains an accurate representation or interpretation of the original material from which the Database was drawn, but neither American Society of Hospital Pharmacists, Inc. nor SilverPlatter International N.V. or its affiliates (collectively, "SilverPlatter") shall be held responsible for any damage, claim or expense incurred by a Subscriber or user as a result of its use or reliance upon the Database.

NEITHER SILVERPLATTER NOR AMERICAN SOCIETY OF HOSPITAL PHARMACISTS, INC. MAKES ANY REPRESENTATIONS OR WARRANTIES, EXPRESS OR IMPLIED, INCLUDING, WITHOUT LIMITATION, WARRANTIES AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE IN CONNECTION WITH THE DATABASE, THE SEARCH AND RETRIEVAL SOFTWARE, THE GUIDE FILES, INDEXES OR SUPPORTING FILES. BOTH SILVERPLATTER AND AMERICAN SOCIETY OF HOSPITAL PHARMACISTS, INC. SPECIFICALLY DISCLAIM ALL SUCH WARRANTIES AND REPRESENTATIONS. NEITHER SILVERPLATTER NOR AMERICAN SOCIETY OF HOSPITAL PHARMACISTS, INC. SHALL BE LIABLE FOR DAMAGES OR OTHER CLAIMS AND DEMANDS ARISING OUT OF USE OF THIS PRODUCT OR THE DATA CONTAINED THEREIN. IN NO EVENT SHALL SILVERPLATTER OR AMERICAN SOCIETY OF HOSPITAL PHARMACISTS, INC. BE LIABLE FOR SPECIAL, CONSEQUENTIAL, EXEMPLARY OR INDIRECT DAMAGES, OR FOR "LOST PROFITS", EVEN IF ADVISED OF THE POSSIBILITY THEREOF.

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Combining Searches

Beginning a search statement with an operator (and, not, or, with, near, or in) automatically combines that statement with the previous one. For instance, if the search you just completed is rheumatoid searching for and arthritis will give you the same results as if you search for rheumatoid and arthritis.

For efficient searching, use the most appropriate operator for your search:

Operator: Example: How it works:
OR memory or abilities Retrieves records that contain either "memory," "abilities," or both.
AND memory and abilities Retrieves records that contain both "memory" and "abilities."
WITH memory with abilities Retrieves records that contain both "memory" and "abilities" in the same field.
NEAR memory near abilities Retrieves records that contain both "memory" and "abilities" in the same sentence.
IN memory in ab Retrieves records that contain "memory" in the AB (Abstract) field.

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Fields in Drug Information Fulltext (DRUG)

Records in Drug Information Fulltext (DRUG) are divided into the following fields. Highlighted fields are limit fields.

Label Field Name   Label Field Name
AF  AHFS Description     IN Investigational Drug ID
AN  AHFS Number   MN  Monograph Number
AR  Abbreviated Name   MT  Monograph Title
BK Book Name   RN  Registry Number
CN Chemical Name     SY Synomn
FT  Full Text   TM Tradename/Manufacturer
GN  Generic Name   UN  Universal Names

There is also a special subset of fields, Citation (CITN), which consists of the AN, AF, BK, GN, MN, MT, and TM fields. Use Citation to display, print, or save only these fields for a set of records.

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Label Field Name
AF AHFS Description
macrolides in af

 

The AHFS Description (AF) field contains the text description of the AHFS Number, which appears in the AHFS Number (AN) field. For example, the AHFS Description for 8.12.12 is "macrolides".

For a list of AHFS Numbers and Descriptions, refer to Classifications.

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AN AHFS Number
12.04 in an
8.12* in an
 

The AHFS Number (AN) field contains the number of the classification name discussed in the record. For example, records discussing penicillins contain 8.12.16 in the AN field.

AHFS Numbers are assigned to AHFS Pharmacologic-Therapeutic Classification Names. The Numbers and Names are listed hierarchically in the Database Table of Contents.

When searching for AHFS numbers, include any periods. You can also use truncation to retrieve a range of codes, as shown above.

For a list of AHFS Numbers and Descriptions, refer to Classifications.

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AR Abbreviated Name
cltn in ar
 

The Abbreviated Name (AR) field contains a common acronym, often derived from the chemical name, which describes the drug.

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BK Book Name (a limit field)
bk=AHFS
injectable in bk
 

The Book Name (BK) field indicates whether the drug monograph is from the AHFS Drug Information or the Handbook on Injectable Drugs (HID).

The BK is a Limit Field. Limit fields, when combined with other search terms, are particularly useful for focusing or limiting a search. To search a limit field, use the in or = operators with the field abbreviation, such as AHFS in bk or bk=AHFS. Omitting the field label retrieves information from free text (non-limit) fields only.

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CN
Chemical Name
6-o-methyl-erythromycin in cn
  The Chemical Name (CN) field contains the chemical name of a drug.
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FT Full Text
311 in ft
lithium toxicity in ft
377 near 355
 

The Full Text (FT) field contains the complete text of drug monographs from both the AHFS and the Handbook on Injectable Drugs (HID) references. The full text is divided into two areas: primary text and additional text. You can view either the primary text or the additional text by selecting it from the lowest level of the document table of contents. The FT field also features two-digit Concept Codes that appear throughout the text in both AHFS and HID records. They are described in more detail below. You can search for any word, phrase, or Concept Code in the FT field. Refer to the Concept Codes, Alphabetically or the Concept Codes, By Subject lists to view the codes and the topic each represents.

Searching With Concept Codes

Two-digit Concept Codes appear enclosed in brackets ([ ]) throughout the full text of records. Each is equivalent to a controlled subject term and precedes a sentence or group of sentences that discuss that subject.

You can use one or more Concept Codes to search for the subject represented, regardless of the wording of the text in which it is found. For example, the search 321 in ft retrieves monographs that discuss some unlabeled investigational use of the drug regardless of whether those terms appear in the full text following the Concept Code. Similarly, by using the near operator, the search 377 near 351 retrieves monographs that discuss both concepts.

Since you search for Concept Codes as a term within the FT field, you can retrieve records that are "false hits." For example, although the search 365 in ft retrieves records of monographs that discuss a fetal toxicity regarding a drug, the search would also retrieve records containing "365 ml."

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GN Generic Name
clarithromycin in gn
 

The Generic Name (GN) field contains the nonproprietary name of a therapeutic substance.

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IN Investigating Drug ID
fk 749 in in
  The Investigating Drug ID (IN) field contains the name that was assigned to a drug during its investigational phase and often appears in early published references. Investigational drug names usually are in alpha-numeric format. Inclusion of this field does not necessarily mean that the drug is currently an investigational drug. Often, the reference is to a name that existed for a drug prior to assigning the USAN (United States Adopted Names) generic name.
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MN Monograph Number
302765 in mn
 

The Monograph Number (MN) field contains a unique number which identifies the monograph.

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MT Monograph Title
erythromycin in mt
  The Monograph Title (MT) field contains the name of the individual drug described in the monograph.
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RN Registry Number
64485-93-4 in rn
64485934 in rn
  The Registry Name (RN) field contains the unique Chemical Abstracts Service (CAS) Registry Number for a drug. You can search in this field with or without hyphens.
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SY Synomn
nightshade in sy
  The Synomn (SY) field contains a synonymous name for generic drug names that are not actual trade names. Synonyms include previous generic names, BAN (British Adopted Names) names, INN (International Nonproprietary Name) names, and other common names (for example, "Deadly Nightshade" is a synonym for "Belladonna").
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TM Tradename/Manufacturer
lopressor in tm
  The Tradename/Manufacturer (TM) field can contain the proprietary name given to the drug by manufacturer and/or the drug manufacturer's name.
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UN Universal Names
demerol in un
  The Universal Names (UN) field combines the Generic Name (GN), Chemical Name (CN), Abbreviated Name (AR), Synonym (SY), and Investigational Drug ID (IN) fields to allow you to research a drug by any of its names.
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CITN Citation
  The Citation (CITN) consists of the following fields. Use the citation to display, print, or save only these fields for a set of records.

Book Name (BK)
AHFS Description (AF)
AHFS Number (AN)
Generic Name (GN)
Monograph Number (MN)
Monograph Title (MT)
Tradename/Manufacturer (TM)
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Classifications

The following codes and corresponding headings are used to group DRUG records by drug classification. You can search for the codes in the AHFS Number (AN) field, such as 4.00 in an, or for the equivalent headings in the AHFS Description (AF) field, such as antihistamine drugs in af.
04:00

Antihistamine Drugs

  36:16 Brucellosis
04:04 First Generation Antihistamines   36:18 Cardiac Function
04:04.04 Ethanolamine Derivatives   36:24 Circulation Time
04:04.08 Ethylenediamine Derivatives   36:26 Diabetes Mellitus
04:04.12 Phenothiazine Derivatives   36:28 Diphtheria
04:04.16 Piperazine Derivatives   36:30 Drug Hypersensitivity
04:04.20 Propylamine Derivatives   36:32 Fungi
04:04.92 Derivatives, Miscellaneous   36:34 Gallbladder Function
04:08 Second Generation Antihistamines   36:36 Gastric Function
04:92 Other Antihistamines   36:38 Intestinal Absorption
08:00 Anti-infective Agents   36:40 Kidney Function
08:08 Anthelmintics   36:44 Liver Function
08:12 Antibacterials   36:48 Lymphogranuloma Venereum
08:12.02 Aminoglycosides   36:52 Mumps
08:12.06 Cephalosporins   36:56 Myasthenia Gravis
08:12.06.04 First Generation Cephalosporins   36:60 Thyroid Function
08:12.06.08 Second Generation Cephalosporins   36:61 Pancreatic Function
08:12.06.12 Third Generation Cephalosporins   36:62 Phenylketonuria
08:12.06.16 Fourth Generation Cephalosporins   36:64 Pheochromocytoma
08:12.07 Miscellaneous Beta-lactams   36:66 Pituitary Function
08:12.07.04 Carbacephems   36:68 Roentgenography
08:12.07.08 Carbapenems   36:72 Scarlet Fever
08:12.07.12 Cephamycins   36:76 Sweating
08:12.07.16 Monobactams   36:80 Trichinosis
08:12.08 Chloramphenicol   36:84 Tuberculosis
08:12.12 Macrolides   36:88 Urine and Feces Contents*
08:12.12.04 Erythromycins   36:88.12 Ketones
8:12.12.12 Ketolides   36:88.20 Occult Blood
08:12.12.92 Other Macrolides   36:88.24 pH
08:12.16 Penicillins   36:88.28 Protein
08:12.16.04 Natural Penicillins   36:88.40 Sugar
08:12.16.08 Aminopenicillins   38:00 Disinfectants (for agents used on objects other than skin)
08:12.16.12 Penicillinase-resistant Penicillins   40:00 Electrolytic, Caloric, and Water Balance
08:12.16.16 Extended-spectrum Penicillins   40:04 Acidifying Agents
08:12.18 Quinolones   40:08 Alkalinizing Agents
08:12.20 Sulfonamides   40:10 Ammonia Detoxicants
08:12.24 Tetracyclines   40:12 Replacement Preparations
08:12.28 Antibacterials, Miscellaneous   40:18 Ion-removing Agents
08:12.28.04 Aminocyclitols   40:18.16 Sodium-removing Agents
08:12.28.08 Bacitracins   40:18.17 Calcium-removing Agents
08:12.28.12 Cyclic Lipopeptides   40:18.18 Potassium-removing Agents
08:12.28.16 Glycopeptides   40:18.19 Phosphate-removing Agents
08:12.28.20 Lincomycins   40:18.92 Other Ion-removing Agents
08:12.28.24 Oxazolidinones   40:20 Caloric Agents
08:12.28.28 Polymyxins   40:24 Salt and Sugar Substitutes
08:12.28.30 Rifamycins   40:28 Diuretics
08:12.28.32 Streptogramins   40:28.10 Potassium-sparing Diuretics
08:12.28.92 Other Miscellaneous Antibacterial Agents   40:36 Irrigating Solutions
08:14 Antifungals   40:40 Uricosuric Agents
08:14.04 Allylamines   44:00 Enzymes
08:14.08 Azoles   48:00 Antitussives, Expectorants, and Mucolytic Agents
08:14.16 Echinocandins   48:08 Antitussives
08:14.28 Polyenes   48:16 Expectorants
08:14.32 Pyrimidines   48:24 Mucolytic Agents
08:14.92 Antifungals, Miscellaneous   52:00 Eye, Ear, Nose, and Throat (EENT) Preparations
08:16 Antimycobacterials   52:02 Antiallergic Agents
08:16.04 Antituberculosis Agents   52:04 Anti-infectives
08:16.92 Antimycobacterials, Miscellaneous   52:04.04 Antibacterials
08:18 Antivirals   52:04.16 Antifungals
08:18.04 Adamantanes   52:04.20 Antivirals
08:18.08 Antiretrovirals   52:04.92 Anti-infectives, Miscellaneous
08:18.08.04 HIV Fusion Inhibitors   52:08 Anti-inflammatory Agents
08:18.08.08 HIV Protease Inhibitors   52:08.08 Corticosteroids
08:18.08.12 Integrase Inhibitors   52:08.20 Nonsteroidal Anti-inflammatory Agents
08:18.08.16 Nonnucleoside Reverse Transcriptase Inhibitors   52:08.92 Anti-inflammatory Agents, Miscellaneous
08:18.08.20 Nucleoside and Nucleotide Reverse Transcriptase Inhibitors   52:10 Carbonic Anhydrase Inhibitors
08:18.08.92 Antiretrovirals, Miscellaneous   52:12 Contact Lens Solutions
08:18.20 Interferons   52:16 Local Anesthetics
08:18.24 Monoclonal Antibodies   52:20 Miotics
08:18.28 Neuraminidase Inhibitors   52:24 Mydriatics
08:18.32 Nucleosides and Nucleotides   52:28 Mouthwashes and Gargles
08:18.92 Antivirals, Miscellaneous   52:32 Vasoconstrictors
08:30 Antiprotozoals   52:92 EENT Drugs, Miscellaneous
08:30.04 Amebicides   56:00 Gastrointestinal Drugs
08:30.08 Antimalarials   56:04 Antacids and Adsorbents
08:30.92 Antiprotozoals, Miscellaneous   56:08 Antidiarrhea Agents
08:36 Urinary Anti-infectives   56:10 Antiflatulents
08:92 Anti-infectives, Miscellaneous   56:12 Cathartics and Laxatives
10:00 Antineoplastic Agents   56:14 Cholelitholytic Agents
12:00 Autonomic Drugs   56:16 Digestants
12:04 Parasympathomimetic (Cholinergic) Agents   56:20 Emetics
12:08 Anticholinergic Agents   56:22 Antiemetics
12:08.04 Antiparkinsonian Agents   56:22.08 Antihistamines
12:08.08 Antimuscarinics/Antispasmodics   56:22.20 5-HT3 Receptor Antagonists
12:12 Sympathomimetic (Adrenergic) Agents   56:22.92 Antiemetics, Miscellaneous
12:16 Sympatholytic (Adrenergic Blocking) Agents   56:24 Lipotropic Agents
12:20 Skeletal Muscle Relaxants   56:28 Antiulcer Agents and Acid Suppressants
12:92 Autonomic Drugs, Miscellaneous   56:28.12 Histamine H2-Antagonists
16:00 Blood Derivatives   56:28.28 Prostaglandins
20:00 Blood Formation and Coagulation   56:28.32 Protectants
20:04 Antianemia Drugs   56:28.36 Proton-pump Inhibitors
20:04.04 Iron Preparations   56:32 Prokinetic Agents
20:04.08 Liver and Stomach Preparations   56:36 Anti-inflammatory Agents
20:12 Coagulants and Anticoagulants   56:92 GI Drugs, Miscellaneous
20:12.04 Anticoagulants   60:00 Gold Compounds
20:12.04.08 Coumarin and Indandione Derivatives   64:00 Heavy Metal Antagonists
20:12.04.16 Heparins   68:00 Hormones and Synthetic Substitutes
20:12.04.92 Anticoagulants, Miscellaneous   68:04 Adrenals
20:12.08 Antiheparin Agents   68:08 Androgens
20:12.12 Coagulants   68:12 Contraceptives
20:12.16 Hemostatics   68:16 Estrogens and Antiestrogens
20:16 Hematopoietic Agents   68:16.04 Estrogens
20:24 Hemorrheologic Agents   68:16.08 Antiestrogens
20:40 Thrombolytic Agents   68:16.12 Estrogen Agonists-Antagonists
24:00 Cardiovascular Drugs   68:18 Gonadotropins
24:04 Cardiac Drugs   68:20 Antidiabetic Agents
24:04.04 Antiarrhythmic Agents   68.20.02 Alpha-glucosidase Inhibitors
24:04.08 Cardiotonic Agents   68.20.04 Biguanides
24:04.92 Cardiac Drugs, Miscellaneous   68:20.08 Insulins
24:06 Antilipemic Agents   68:20.16 Meglitinides
24:06.04 Bile Acid Sequestrants   68:20.20 Sulfonylureas
24:06.06 Fibric Acid Derivatives   68:20.28 Thiazolidinediones
24:06.08 HMG-CoA Reductase Inhibitors   68:20.92 Antidiabetic Agents, Miscellaneous
24:06.92 Antilipemic Agents, Miscellaneous   68:22 Antihypoglycemic Agents
24:08 Hypotensive Agents   68:22.12 Glycogenolytic Agents
24:08:16 Central Alpha-agonists   68:22.92 Antihypoglycemic Agents, Miscellaneous
24:08.20 Direct Vasodilators   68:24 Parathyroid
24:08.32 Peripheral Adrenergic Inhibitors   68:28 Pituitary
24:08.92 Hypotensive Agents, Miscellaneous   68:30 Somatotropin Agonists and Antagonists
24:12 Vasodilating Agents   68:30.04 Somatotropin Agonists
24:12.08 Nitrates and Nitrites   68:30.08 Somatotropin Antagonists
24:12.12 Phosphodiesterase Inhibitors   68:32 Progestins
24:12.92 Vasodilating Agents, Miscellaneous   68:34 Other Corpus Luteum Hormones
24:16 Sclerosing Agents   68:36 Thyroid and Antithyroid Agents
24:20 Alpha-adrenergic Blocking Agents   68:36.04 Thyroid Agents
24:24 Beta-adrenergic Blocking Agents   68:36.08 Antithyroid Agents
24:28 Calcium-Channel Blocking Agents   72:00 Local Anesthetics
24:28.08 Dihydropyridines   76:00 Oxytocics
24:28.92 Calcium-Channel Blocking Agents, Miscellaneous   78:00 Radioactive Agents
24:32 Renin-Angiotensin-Aldosterone System Inhibitors   80:00 Serums, Toxoids, and Vaccines
24:32.04 Angiotensin-Converting Enzyme Inhibitors   80:04 Serums
24:32.08 Angiotensin II Receptor Antagonists   80:08 Toxoids
24:32.20 Mineralocorticoid (Aldosterone) Receptor Antagonists   80:12 Vaccines
28:00 Central Nervous System Agents   84:00 Skin and Mucous Membrane Agents
28:04 General Anesthetics   84:04 Anti-infectives
28:08 Analgesics and Antipyretics   84:04.04 Antibacterials
28:08.04 Nonsteroidal Anti-inflammatory Agents   84:04.06 Antivirals
28:08.04.08 Cyclooxygenase-2 (COX-2) Inhibitors   84:04.08 Antifungals
28:08.04.24 Salicylates   84:04.08.04 Allylamines
28:08.04.92 Other Nonsteroidal Anti-inflammatory Agents   84:04.08.08 Azoles
28:08.08 Opiate Agonists   84:04.08.12 Benzylamines
28:08.12 Opiate Partial Agonists   84:04.08.16 Echinocandins
28:08.92 Analgesics and Antipyretics, Miscellaneous   84:04.08.20 Hydroxypyridones
28:10 Opiate Antagonists   84:04.08.28 Polyenes
28:12 Anticonvulsants   84:04.08.32 Pyrimidines
28:12.04 Barbiturates   84:04.08.40 Thiocarbamates
28:12.08 Benzodiazepines   84:04.08.92 Antifungals, Miscellaneous
28:12.12 Hydantoins   84:04.12 Scabicides and Pediculicides
28:12.16 Oxazolidinediones   84:04.92 Local Anti-infectives, Miscellaneous
28:12.20 Succinimides   84:06 Anti-inflammatory Agents
28:12.92 Anticonvulsants, Miscellaneous   84:08 Antipruritics and Local Anesthetics
28:16 Psychotherapeutic Agents   84:12 Astringents
28:16.04 Antidepressants   84:16 Cell Stimulants and Proliferants
28:16.04.12 Monoamine Oxidase Inhibitors   84:20 Detergents
28:16.04.20 Selective-serotonin Reuptake Inhibitors   84:24 Emollients, Demulcents, and Protectants
28:16.04.24 Serotonin Modulators   84:24.04 Basic Lotions and Liniments
28:16.04.28 Tricyclics and Other Norepinephrine-reuptake Inhibitors   84:24.08 Basic Oils and Other Solvents
28:16.04.92 Antidepressants, Miscellaneous   84:24.12 Basic Ointments and Protectants
28:16.08 Antipsychotics   84:24.16 Basic Powders and Demulcents
28:16.08.04 Atypical Antipsychotics   84:28 Keratolytic Agents
28:16.08.08 Butyrophenones   84:32 Keratoplastic Agents
28:16.08.24 Phenothiazines   84:50 Depigmenting and Pigmenting Agents
28:16.08.32 Thioxanthenes   84:50.04 Depigmenting Agents
28:16.08.92 Antipsychotics, Miscellaneous   84:50.06 Pigmenting Agents
28:16.12 Psychotherapeutic Agents, Miscellaneous   84:80 Sunscreen Agents
28:20 Anorexigenic Agents and Respiratory and Cerebral Stimulants   84:92 Skin and Mucous Membrane Agents, Miscellaneous
28:24 Anxiolytics, Sedatives, and Hypnotics   86:00 Smooth Muscle Relaxants
28:24.04 Barbiturates   86:08 Gastrointestinal Smooth Muscle Relaxants
28:24.08 Benzodiazepines   86:12 Genitourinary Smooth Muscle Relaxants
28:24.92 Anxiolytics, Sedatives, and Hypnotics; Miscellaneous   86:16 Respiratory Smooth Muscle Relaxants
28:28 Antimanic Agents   88:00 Vitamins
28:32 Antimigraine Agents   88:04 Vitamin A
28:32.28 Selective Serotonin Agonists   88:08 Vitamin B Complex
28:32.92 Antimigraine Agents, Miscellaneous   88:12 Vitamin C
28:92 Central Nervous System Agents, Miscellaneous   88:16 Vitamin D
32:00 Contraceptives (foams, devices)   88:20 Vitamin E
34:00 Dental Agents   88:24 Vitamin K Activity
36:00 Diagnostic Agents   88:28 Multivitamin Preparations
36:04 Adrenocortical Insufficiency   92:00 Miscellaneous Therapeutic Agents
36:08 Amyloidosis   94:00 Devices
36:12 Blood Volume   96:00 Pharmaceutical Aids

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Concept Codes, Alphabetically

Two-digit Concept Codes appear in brackets ([ ]) throughout the full text of each record. The codes are drawn from the Handbook on Injectable Drugs (HID) and the AHFS Drug Information, and are used to group documents by subject matter. Each code is equivalent to a controlled subject term and precedes a sentence or group of sentences that discuss that subject.

You can search for a specific code, or for a range of codes using truncation. Refer to the Full Text (FT) field description for additional information regarding searching with Concept Codes.

[81]  Absorption   [76] Lab Test Interference
[00.8]  Active Metabolite   [87] Lactation
[36] Additive Compatibility   [48] Legal Description
[57] Administration/Route   [24] Mechanism of Action
[60] Adverse Reaction (Side Effect)   [23] Methodology
[55] Age/Dose Relation   [26] Microbiology (general)
[84] Biopharmaceutics (Effect of Form)   [21] Nonapproved or Investigational Use
[85] Blood or CSF Level   [17] Osmolarity/Osmolality
[66] Carcinogenicity and Mutagenicity   [41] Other Chemical, Ion, or Ingredient
[11] Chemical Description   [15] pH
[10] Chemistry   [80] Pharmacokinetics (ADME)
[42] Combination   [13] Physical Description
[12] Constants (pKa, ionization, etc)   [56] Physiological Defect/Dosage (hepatic/renal)
[44] Container (discussion)   [88] Placental Transfer
[38] Container Compatibility   [64] Precautions and contraindications/Advice to Patients
[46] Contamination   [40] Preparation (Dosage Form)
[90] Cross References   [05] Product Specific Information
[63] Dependence Addiction   [45] Reconstitution (technique)
[82] Distribution   [00.3] Reference to concurrent therapy with another drug
[50] Dosage and Administration   [28] Resistance and Cross Resistance
[58] Dosage Equivalency   [47] Route
[43] Dosage Form, Strength, Concentration   [62] Sensitivity (allergies, photosens., etc.)
[52] Dosage Regimen   [14] Solubility
[32] Drug Compatibility   [51] Special Instructions
[77] Drug Interaction   [27] Spectrum (definitive)
[25] Effect of Age   [30] Stability
[83] Elimination   [34] Storage and environment
[31] Expiration Date Description   [18] Structure/Activity
[65] Fetal Toxicity   [37] Syringe Additive
[35] Filter, adm. Set compatibility   [15] Temperature (Melting Point, etc)
[78] Food Interaction   [20] Therapy, Pharmacotherapy, Microbiology
[00.1] Generic Drug Name   [22] Therapy/Use
[71] Interaction Mechanism   [61] Toxicity
[70] Interactions   [68] Treatment (and Antidote)
[86] Kinetics   [33] Vehicle Compatibility

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Concept Codes, By Subject

Two-digit Concept Codes appear in brackets ([ ]) throughout the full text of each record. The codes are drawn from the Handbook on Injectable Drugs (HID) and the AHFS Drug Information, and are used to group documents by subject matter. Each code is equivalent to a controlled subject term and precedes a sentence or group of sentences that discuss that subject.

You can search for a specific code, or for a range of codes using truncation. Refer to the Full Text (FT) field description for additional information regarding searching with Concept Codes.

 

Nonmonograph Drug Information
[00.1] Generic Drug Name   [00.3] Reference to concurrent therapy with another drug
[00.8] Active Metabolite   [05] Product Specific Information
 
Chemistry
[10] Chemistry   [14] Solubility Dissolution
[11] Chemical Description   [15] pH
[12] Constants (pKa, ionization, etc)   [15] Temperature (Melting Point, etc)
[13] Physical Description   [17] Osmolarity, Osmolality
[14] Solubility   [18] Structure/Activity
 
Therapy, Pharmacology, Microbiology
[20] Use Therapy, Pharmacotherapy, Microbiology   [25] Effect of Age
[21] Nonapproved or Investigational Use   [26] Microbiology (general)
[22] Therapy/Use   [27] Spectrum (definitive)
[23] Methodology   [28] Resistance and cross resistance
[24] Mechanism of Action    
 
Stability
[30] Stability   [35] Filter, adm. Set Compatibility
[31] Expiration Date Description   [36] Additive Compatibility
[32] Drug Compatibility   [37] Syringe Additive
[33] Vehicle Compatibility   [38] Container Compatibility
[34] Storage and Environment    
 
Preparations
[40] Preparation (Dosage Form)   [45] Reconstitution
[41] Other Chemical, Ion, or Ingredient   [46] Contamination
[42] Combination (technique)   [47] Route
[43] Dosage Form, Strength, Concentration   [48] Legal Description
[44] Container (discussion)    
 
Dosage and Administration
[50] Dosage and Administration   [56] Physiological Defect/Dosage (Hepatic/Renal)
[51] Special Instructions   [57] Administration/Route
[52] Dosage Regimen   [58] Dosage Equivalency
[55] Age/Dose Relation
 
Toxicity
[60] Adverse Reaction (Side Effect)   [64] Precaution and Contraindication/Advice to Patients
[61] Toxicity   [65] Fetal Toxicity
[62] Sensitivity (Allergies, Photosens., etc.)   [66] Carcinogenicity and Mutagenicity
[63] Dependence and Addiction   [68] Treatment (and antidote)
 
Interactions
[70] Interactions   [77] Drug Interaction
[71] Interaction Mechanism   [78] Food Interaction
[76] Lab Test Interference
 
Pharmacokinetics (ADME) [80] Pharmacokinetics (ADME) [85] Blood or CSF Level
[81] Absorption   [86] Kinetics
[82] Distribution   [87] Lactation
[83] Elimination   [88] Placental Transfer
[84] Biopharmaceutics (Effect of Form)
 
Cross References
[90] Cross references

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Finding Word Variants

You can use the truncation symbol (*) as a substitute for any string of zero or more characters in your search term. For example, the search 37* retrieves any record containing "370", "371", "376", "377", or "378", the Concept Codes for Interactions.

Using Truncation (*)
Use the truncation symbol (*) as a substitute for any string of zero or more characters in your search term. For example, the search robot* retrieves any record containing "robot," "robots," "robotics," etc. You can use the truncation symbol anywhere in your search term, except as the first character.

Using Wildcards (?)
Use the wildcard symbol (?) as a substitute for one character or none. For example, the search m?cdonald retrieves records containing "McDonald" or "MacDonald." You can use the wildcard symbol anywhere in your search term, except as the first character.

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Stopwords

Words of little intrinsic meaning that occur too frequently to be useful in searching text are known as "stopwords." You cannot search for the following stopwords by themselves, but you can include them within phrases:

about be for in of than to who
also been from into on the was with
an but had is only there were  
and by has it or these when  
are either have its other this which  
at et-al having not some those while  

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Table of Contents

The DIF Database Table of Contents consists of 5 levels. There are four levels of AHFS Classifications and a fifth level of monograph titles.

The Table of Contents for each document consists of a Profile, which provides summary information about the document; and any section heading, sub-heading, table heading, or other heading that appears in the text of the document.

Refer to SPIRS Help for information on using the Table of Contents.

AHFS Document Headings

The following headings can appear in the tables of contents of AHFS documents. Not all headings necessarily appear in each document.

Acute Toxicity
Additional Information
Cautions
Chemistry
Chemistry and Stability
Chronic Toxicity
Dosage and Administration
Drug Interactions
Introduction
Laboratory Test Interferences
Mechanism of Action
Pharmacokinetics
Pharmacology
Preparations
Profile
References
Resistance
Spectrum
Uses

HID Document Headings

The following headings can appear in the tables of contents of HID documents. Not all headings necessarily appear in each document.

Additional Compatibility Information
Compatibility Information
Dosage
Other Information
Products
Profile
References
Stability

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Using Limit Fields

Limit fields are specially-indexed fields that enable you to focus a search to records of documents with a specific characteristic such as publication year or language of text. They are particularly useful when combined with other search terms. Always use the field abbreviation along with in or = operators to search a limit field, such as 200312 in si or si=200312.

BMDS Limit (BD)
Source Code Index (SI)
Update Code (UD)

For limit fields containing numeric data, you can also use other special operators to retrieve a range of data within a specific field:
Symbol Operation Performed Example
<
less than ud<200312  
>
greater than  ud>200312  
<=
less than or equal to ud<=200312
>=
greater than or equal to ud>=200312  
-
within a range ud>ud=200312-200401 

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Search Examples

The following examples demonstrate how to search the database. These examples are not exhaustive, but do illustrate several search techniques. It is important to note that, although all examples are given in lowercase, SPIRS is not case-sensitive; whether your search terms are entered in upper- or lower-case, the same records will be retrieved.

To find all occurrences of "adrenals" in the AHFS Description (AF) field, type adrenals in af.

To find all documents that mention both "soluble" and "tartrates", type soluble and tartrates.

To find all documents that contain "amphotericin-b" in the Generic Name (GN) field, type amphotericin-b in gn.

Refer to the SPIRS Help for more information on using the Index or Table of Contents.

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Guide Revised August 3, 2006

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