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HCT publishes the results of therapeutic clinical trials (all phases), meta-analysis, methodological papers, review articles, outcomes of clinical research and treatment, quality of life research, pharmacoeconomic evaluation, controversies, invited editorial comments, book and software reviews, news, letters to the editor, abstracts of conferences, and pilot studies. HCT will also consider negative results from appropriate, sufficiently powered studies as well as manuscripts that are primarily methodological on the theory and practice of clinical trials.
Occasional special issues or supplements to HCT are produced to publish the proceedings of outstanding meetings or to explore an important topic in depth. All manuscripts are reviewed by the editor and at least two outside reviewers for clinical relevance, originality, scientific quality, and statistical techniques.





