Acute Thrombosis of Double Major Coronary Arteries Associated with Amphetamine Abuse

Lan, Wei-Ren
Yeh, Hung-I
Hou, Charles Jia-Yin
Chou, Yu-San

Division of Cardiology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.

Received: November 8, 2006 Accepted: December 14, 2006

Address correspondence and reprint requests to: Dr. Leonard Wei-Ren Lan, M.D., Division of Cardiology, Department of Internal Medicine, Mackay Memorial Hospital, No. 92, Chung Shan North Rd., Sec. 2, Taipei, Taiwan. Tel: 886-2-2543-3535 ext. 2456; Fax: 886-2-2543-3642; E-mail: [email protected]

Acta Cardiologica Sinica 23(4):p 268-272, December 2007.

Drug-induced acute myocardial infarction is not a common phenomenon. The underlying mechanism in the majority of such patients has been related to coronary spasm, including in those with amphetamine abuse, in whom the coronary arteriogram was always found normal. We report a 30-year-old male amphetamine abuser with acute myocardial infarction owing to acute thrombosis of the left anterior descending coronary artery and left circumflex coronary artery. We postulate a relationship between the use of amphetamine and occurrence of acute thrombosis of multiple major coronary arteries.