Hypertonic saline use in neurocritical care for treating cerebral edema

A review of optimal formulation, dosing, safety, administration and storage

Holden, Devin N PharmD, BCPS, BCCCP
Mucksavage, Jeffrey J PharmD, FNCS, BCPS
Cokley, John A PharmD, BCPPS
Kim, Keri S PharmD, MS CTS, BCPS
Tucker, Natalie L PharmD, BCCCP
Esordi, Molly S PharmD
Cook, Aaron M PharmD

Albany Medical Center Hospital, Albany, NY, USA
University of Illinois Chicago College of Pharmacy, Chicago, IL, USA
Texas Children’s Hospital, Baylor College of Medicine, Houston, TX, USA
University of Illinois Health, Chicago, IL, USA
Ochsner Medical Center, New Orleans, LA, USA
Texas Children’s Hospital, Houston, TX, USA
University of Kentucky Chandler Medical Center, Lexington, KY, USA

Address correspondence to Dr. Holden ([email protected]).

Revised December 30, 2022

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/pages/standard-publication-reuse-rights)

American Journal of Health-System Pharmacy 80(6):p 331-342, March 15, 2023. | DOI: 10.1093/ajhp/zxac368