Dissecting the phenotype in genome-wide association studies of psychiatric illness

  • Craddock, Nick PhD, FRCPsych
  • Kendler, Kenneth MD
  • Neale, Michael PhD
  • Nurnberger, John MD, PhD
  • Purcell, Shaun PhD
  • Rietschel, Marcella MD
  • Perlis, Roy MD
  • Santangelo, Susan L. ScD
  • Schulze, Thomas MD
  • Smoller, Jordan W. MD, PhD
  • Thapar, Anita PhD, FRCPsych
British Journal of Psychiatry 195(2):p 97-99, August 2009.

Summary

Over the past 2 years genome-wide association studies have made major contributions to understanding the genetic architecture of many common human diseases. This editorial outlines the development of such studies in psychiatry and highlights the opportunities for advancing understanding of the biological underpinnings and nosological structure of psychiatric disorders.

Declaration of interest

None.

Copyright © 2009 The Royal College of Psychiatrists