Sertraline reduced the severity of patients’ depressive symptoms in major depressive disorderEfficacy of sertraline in the treatment of children and adolescents with major depressive disorder: two randomized controlled trials.

Wagner KD, Ambrosini P, Rynn M, et al. Efficacy of sertraline in the treatment of children and adolescents with major depressive disorder: two randomized controlled trials. JAMA 2003; ; 290: 1033–41.WagnerKDAmbrosiniPRynnMet alEfficacy of sertraline in the treatment of children and adolescents with major depressive disorder: two randomized controlled trials.JAMA20032901033-41Q In children and adolescents with major depressive disorder (MDD), is sertraline more effective than placebo for reducing the severity of patients’ depressive symptoms?

For correspondence: Dr K D Wagner, University of Texas Medical Branch, Galveston, TX, USA. [email protected]

Source of funding: Pfizer Inc.