Oestrogen plus progestogen did not reduce the risk of coronary heart disease in postmenopausal womenEstrogen plus progestin and the risk of coronary heart disease.

Crandall, Carolyn MD (commentator)
Manson, JE
Hsia, J
Johnson, KC
et al,

University of California, Los Angeles Los Angeles, California, USA

Manson JE, Hsia J, Johnson KC, et al. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med 2003; 349: 523–34.MansonJEHsiaJJohnsonKCet alEstrogen plus progestin and the risk of coronary heart disease.N Engl J Med2003349523-34Q In postmenopausal women, how does oestrogen plus progestogen influence the risk of coronary heart disease (CHD)?

For correspondence: Dr J E Manson, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA. [email protected]

Source of funding: National Heart, Lung and Blood Institute.

Evidence Based Medicine 9(2):p 52, April 2004.

Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★★☆☆ Endocrine ★★★★★☆☆ Cardiology ★★★★★☆☆