Short course nevirapine was better than zidovudine for reducing the risk of mother to child transmission of HIV-1 infectionIntrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial.

King, Susan MD (commentator)
Jackson, JB
Musoke, P
Fleming, T
et al,

Hospital for Sick Children and University of Toronto Toronto, Ontario, Canada

Jackson JB, Musoke P, Fleming T, et al. Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial. Lancet 2003; 362: 859–68.JacksonJBMusokePFlemingTet alIntrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial.Lancet2003362859-68Q In pregnant women with HIV-1 infection, is short course nevirapine more effective than a short zidovudine regimen for reducing the risk of mother to child transmission of HIV-1 infection?

For correspondence: Dr J B Jackson, Johns Hopkins School of Medicine, Baltimore, MD, USA. [email protected]

Source of funding: HIVNET; NIAID; NIH; DHHS and HPTN.

Evidence Based Medicine 9(2):p 53, April 2004.