Penicillin V did not shorten symptoms in children with sore throatPenicillin for acute sore throat in children: randomised, double blind trial.

Lindbaek, Morten MD (commentator)
Zwart, S
Rovers, MM
de Melker, RA
et al,

University of Oslo Oslo, Norway

Zwart S, Rovers MM, de Melker RA, et al. Penicillin for acute sore throat in children: randomised, double blind trial. BMJ 2003; 327: 1324–7.ZwartSRoversMMde MelkerRAet alPenicillin for acute sore throat in children: randomised, double blind trial.BMJ20033271324-7Q In children 4–15 years of age with a sore throat, is penicillin V (PCV) for 3 (PCV3) or 7 (PCV7) days more effective than placebo for reducing the duration of symptoms (DOS)?

For correspondence: Dr S Zwart, Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands. [email protected]

Sources of funding: Groene Land Achmea Health Insurances and Stichting Gezondheidszorgonderzoek Ysselmond.

Evidence Based Medicine 9(3):p 77, May-June 2004.

Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ Paediatrics ★★★★★☆☆