Isosorbide dinitrate plus hydralazine was effective for advanced heart failure in black patientsCombination of isosorbide dinitrate and hydralazine in blacks with heart failure.

Massie, Barry M MD (commentator)
Taylor, AL
Ziesche, S
Yancy, C
et al,

University of California, San Francisco; San Francisco, California, USA

Taylor AL, Ziesche S, Yancy C, et al. Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. N Engl J Med 2004; 351: 2049–57.TaylorALZiescheSYancyCet alCombination of isosorbide dinitrate and hydralazine in blacks with heart failure.N Engl J Med20043512049-57Q In black patients with New York Heart Association (NYHA) class III or IV heart failure (HF) with dilated ventricles, is a fixed dose of isosorbide dinitrate plus hydralazine (ID+H) better than placebo?

For correspondence: Dr A Taylor, University of Minnesota Medical School, Minneapolis, MN, USA. [email protected]

Source of funding: NitroMed.

Evidence Based Medicine 10(2):p 44, April 2005.

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★☆☆ Internal medicine ★★★★★☆☆ Cardiology ★★★★★★☆