Pulmonary vein isolation was better than antiarrhythmic drugs for symptomatic atrial fibrillationRadiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation: a randomized trial.

Wyse, D George MD, PhD (commentator)
Wazni, OM
Marrouche, NF
Martin, DO
et al,

Libin Cardiovascular Institute of Alberta Calgary, Alberta, Canada

Wazni OM, Marrouche NF, Martin DO, et al. Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation: a randomized trial. JAMA 2005; 293:2634–40.WazniOMMarroucheNFMartinDOet alRadiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation: a randomized trial.JAMA20052932634-40Q In patients with symptomatic atrial fibrillation (AF), is pulmonary vein isolation (PVI) with radiofrequency ablation more effective than antiarrhythmic drugs as first line treatment?

For correspondence: Dr A Natale, Cleveland Clinic Foundation, Cleveland, OH, USA. [email protected]

Source of funding: Acuson (division of Siemens Medical Solutions).

Evidence Based Medicine 11(1):p 16, February 2006.

Clinical impact ratings Internal medicine ★★★★★★☆ Cardiology ★★★★★★★