Oestrogen therapy increased stroke risk and decreased hip fracture risk but did not affect coronary heart disease risk in postmenopausal women with prior hysterectomyEffects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Womens Health Initiative randomized controlled trial.

Thacker, Holly L MD, FACP (commentator)
Anderson, GL
Limacher, M
Assaf, AR
et al,

Cleveland Clinic Foundation Women’s Health Center Cleveland, Ohio, USA

Anderson GL, Limacher M, Assaf AR, et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women’s Health Initiative randomized controlled trial. JAMA 2004; 291:1701–12.AndersonGLLimacherMAssafARet alEffects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Womens Health Initiative randomized controlled trial.JAMA20042911701-12Q In postmenopausal women with prior hysterectomy, what is the effect of conjugated equine oestrogen (CEE) on major disease rates?

For correspondence: Dr G L Anderson, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. [email protected]

Source of funding: National Heart, Lung, and Blood Institute.

Evidence Based Medicine 9(6):p 184, November-December 2004.

Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★★★☆ Endocrine ★★★★★★☆ Gynaecology ★★★★★☆☆