Carvedilol reduced mortality and hospital admission in severe chronic heart failure, regardless of pretreatment systolic BPInfluence of pretreatment systolic blood pressure on the effect of carvedilol in patients with severe chronic heart failure: the Carvedilol Prospective Randomized Cumulative Survival COPERNICUS study.

Rouleau JL, Roecker EB, Tendera M, et al. Influence of pretreatment systolic blood pressure on the effect of carvedilol in patients with severe chronic heart failure: the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) study. J Am Coll Cardiol 2004; 43: 1423–9.RouleauJLRoeckerEBTenderaMet alInfluence of pretreatment systolic blood pressure on the effect of carvedilol in patients with severe chronic heart failure: the Carvedilol Prospective Randomized Cumulative Survival COPERNICUS study.J Am Coll Cardiol2004431423-9Q How does pretreatment systolic blood pressure (SBP) affect the efficacy and safety of carvedilol in patients with severe chronic heart failure (HF)?

For correspondence: Dr J L Rouleau, Université de Montréal, Montréal, Québec, Canada. [email protected]

Source of funding: not stated.