Parenteral artesunate reduced inhospital mortality more than quinine in severe falciparum malariaArtesunate versus quinine for treatment of severe falciparum malaria: a randomised trial.

Victor, Gary MB, FRCPC (commentator)
Dondorp, A
Nosten, F
Stepniewska, K
et al,

Ottawa Hospital-General Campus, Ottawa, Ontario, Canada

Dondorp A, Nosten F, Stepniewska K, et al. Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet 2005; 366:717–25.DondorpANostenFStepniewskaKet alArtesunate versus quinine for treatment of severe falciparum malaria: a randomised trial.Lancet2005366717-25Q What is the relative effectiveness of parenteral artesunate and parenteral quinine for patients with severe falciparum malaria?

For correspondence: Professor N J White, Mahidol University, Bangkok, Thailand. [email protected]

Source of funding: Wellcome Trust.

Evidence Based Medicine 11(2):p 52, April 2006.

Clinical impact ratings Infectious disease ★★★★★★☆ Tropical & travel medicine ★★★★★★☆