Geriatric Frailty Is Associated With Oxidative Stress, Accumulation, and Defective Repair of DNA Double-Strand Breaks Independently of Age and Comorbidities

  • Kravvariti, Evrydiki MD
  • Ntouros, Panagiotis A MD
  • Vlachogiannis, Nikolaos I MD
  • Pappa, Maria MD
  • Souliotis, Vassilis L PhD
  • Sfikakis, Petros P MD

  • Postgraduate Medical Studies in Geriatric Syndromes and Physiology of Aging, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

    First Department of Propaedeutic Internal Medicine and Joint Academic Rheumatology Program, National and Kapodistrian University of Athens Medical School, Athens, Greece

    First Department of Propaedeutic Internal Medicine and Joint Academic Rheumatology Program, National and Kapodistrian University of Athens Medical School, Athens, Greece

    First Department of Propaedeutic Internal Medicine and Joint Academic Rheumatology Program, National and Kapodistrian University of Athens Medical School, Athens, Greece

    First Department of Propaedeutic Internal Medicine and Joint Academic Rheumatology Program, National and Kapodistrian University of Athens Medical School, Athens, Greece

    First Department of Propaedeutic Internal Medicine and Joint Academic Rheumatology Program, National and Kapodistrian University of Athens Medical School, Athens, Greece

    Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece

    Postgraduate Medical Studies in Geriatric Syndromes and Physiology of Aging, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

    First Department of Propaedeutic Internal Medicine and Joint Academic Rheumatology Program, National and Kapodistrian University of Athens Medical School, Athens, Greece

Address for correspondence: Evrydiki Kravvariti, MD, PhD, First Department of Propaedeutic Internal Medicine and Joint Academic [LINE SEPARATOR]Rheumatology Program, National and Kapodistrian University of Athens Medical School, 75, Mikras Asias St, 11527, Athens, Greece. E-mail: [email protected]

Received June 26, 2022

Revised March 30, 2023

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Journals of Gerontology Series A: Biological Sciences and Medical Sciences 78(4):p 603-610, April 2023. | DOI: 10.1093/gerona/glac214
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