Pilot evidence that topically applied triiodothyronine can stimulate hair growth in human scalp skin

Gherardini, Jennifer Data curation; Formal analysis; Writing - review & editing
Akhundlu, Aysun Data curation; Formal analysis; Writing - review & editing
Gompels, Matthew Data curation; Formal analysis; Writing - review & editing
Verbinnen, Andrew Data curation; Formal analysis; Writing - review & editing
Velasco, Sergi Data curation; Formal analysis; Writing - review & editing
Knie, Ulrich Methodology; Writing - review & editing
Kassir, Ramtin Resources; Writing - review & editing
Chéret, Jérémy Conceptualization; Data curation; Formal analysis; Supervision; Writing - review & editing
Paus, Ralf Conceptualization; Funding acquisition; Supervision; Writing - original draft

CUTANEON – Skin and Hair Innovations, Hamburg and Berlin, Germany
Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
HairDAO, West Palm Beach, FL, USA
Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
CUTANEON – Skin and Hair Innovations, Hamburg and Berlin, Germany
Kassir Plastic Surgery, New York, NY, USA
CUTANEON – Skin and Hair Innovations, Hamburg and Berlin, Germany
Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
CUTANEON – Skin and Hair Innovations, Hamburg and Berlin, Germany
Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA

Correspondence: Ralf Paus. Email: [email protected]

Conflicts of interest: HairDAO and CUTANEON have filed a patent application related to the current study (WO2024124206A1). J.G., J.C., R.P. and U.K. work or consult for CUTANEON, and A.V. works for HairDAO. The other authors declare no conflicts of interest.

Received February 17, 2025

Accepted April 21, 2025

Revised May 28, 2025

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/pages/standard-publication-reuse-rights)

Clinical & Experimental Dermatology 50(9):p 1862-1864, September 2025. | DOI: 10.1093/ced/llaf190