Comparison of the Inverness Medical Acceava Strep A Test With the Genzyme OSOM and Quidel QuickVue Strep A Tests

Rogo, Tanya MD
Schwartz, Richard H. MD
Ascher, David P. MD

¹Inova Fairfax Hospital for Children, Falls Church, VA, USA

Corresponding Author: Richard H. Schwartz, 100 East Street SE, Suite 301, Vienna, VA 22180, USA

Clinical Pediatrics 49(11):p 1050-1052, November 2010. | DOI: 10.1177/0009922810376235

Abstract

Previous studies of the accuracy of rapid in-office tests for group A Streptococcus had disparate results, ranging from sensitivity of 70% to more than 90%. The sensitivity and specificity of 3 commercially available Strep A tests were determined in 2 private pediatric office settings. Acceava Strep A, Genzyme OSOM Strep A, and the Quidel QuickVue Strep A tests were the representative rapid tests for detection of Streptococcus pyogenes. Overnight culture on standard 5% sheep blood agar was the reference standard for this study. All 3 CLIA (Clinical Laboratory Improvement Amendments)-waived tests had sensitivities and specificities that exceeded 95%.