Safety evaluation of intra-articular sodium hyaluronate for the treatment of chondromalacia patellae

In recent years, with the deeper understanding of the physical and chemical properties of sodium hyaluronate, physiological role in vivo has been more comprehensive understood. A large number of studies have shown that endogenous sodium hyaluronate can play an important role in protecting joints through a variety of mechanisms; and the role of exogenous hyaluronic acid in treating ostarthritis has been widely recognized. As the clinical studies developing, people try to introduce intra-articular sodium hyaluronate to treat chondromalacia patella, which receives good effects. At present, there are some studies talking about the indications, contraindications and safety of intra-articular sodium hyaluronate, but we need to carry out a large-scale, randomized, controlled clinical study to develop standardized and uniform treatment programs.