Latest Therapeutics Developments for Pancreatic Cancer

  • Sheldon, Katherine Ph.D.
Drug & Market Development 15(3):p 429-433, March 2004.

• Pancreatic cancer is a disease with a dismal prognosis. Ranking as the fourth leading cause of cancer death in the U.S., no effective treatments exist, and overall survival expectation is less than 4%.

• Pancreatic tumors are refractory to many conventional chemotherapies, limiting the options available to newly diagnosed patients. The only potentially curative treatment is surgery; unfortunately, most cases of pancreatic cancer are diagnosed in later stages of the disease when systemic therapies offer the only potential for remission.

• The pipeline of novel therapies for pancreatic cancer contains many promising compounds in late-stage clinical development. The majority of these compounds utilize novel approaches to therapy such as immune stimulation or gene therapy, and, as such, have produced encouraging results in this hard to treat disease.

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