Oral nalmefene reduced relapse to heavy drinking and was well tolerated in patients with alcohol dependence

Mason BJ, Salvato FR, Williams LD, et al. A double-blind, placebo-controlled study of oral nalmefene for alcohol dependence. Arch Gen Psychiatry 1999 Aug;56:719–24.

Source of funding: in part, National Institute on Alcohol abuse and Alcoholism; the study drugs were provided by Ivax Corporation, Miami, FL, USA.

For correspondence: Dr B J Mason, University of Miami, Department of Psychiatry, Alcohol Disorders Research Unit, 1400 NW 10th Avenue, Suite 307A, Miami, FL 33136, USA. Fax +1 305 243 2599.