Office based treatment with buprenorphine plus naloxone, or buprenorphine alone reduces opiate use and cravingOffice-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone.

  • Gowing, Linda R PhD (commentator)
  • Lopatko, Olga MD PhD (commentator)
  • Fudala, PJ
  • Bridge, TP
  • Herbert, S
  • et al,

  • Department of Clinical and Experimental Pharmacology, University of Adelaide, Adelaide, South Australia, Australia

Fudala PJ, Bridge TP, Herbert S, et al. Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone. N Engl J Med 2003; 349: 949–58.FudalaPJBridgeTPHerbertSet alOffice-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone.N Engl J Med2003349949-58Q How effective is buprenorphine with or without naloxone in reducing opiate use and craving in people addicted to opiates?

For correspondence: Dr P Fudala, Psychiatry Service, VA Medical Center, University and Woodland Avenues, Philadelphia, USA

Sources of funding: National Institute on Drug Abuse through the Department of Veterans Affairs Cooperative Studies Program.

Evidence-Based Mental Health 7(2):p 54, May 2004.
Copyright © 2004 by BMJ Publishing Group Ltd, Royal College of Psychiatrists, & British Psychological Society