Review: relying on published data alone overestimates efficacy and safety of SSRIs in childrenSelective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data.

Wolraich, Mark L MD (commentator)
Whittington, CJ
Kendall, T
Fonagy, P
et al,

CMRI/Shaun Walters Professor of Pediatrics, OU Child Study Center, Oklahoma City, OK, USA

Whittington CJ, Kendall T, Fonagy P, et al. Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. Lancet 2004; 363: 1341–5.WhittingtonCJKendallTFonagyPet alSelective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data.Lancet20043631341-5 Q Does the risk-benefit profile of selective serotonin reuptake inhibitors (SSRIs) in the treatment of depression in children change when unpublished data is added to the meta-analysis?

For correspondence: Craig Whittington, Centre for Outcomes Research and Effectiveness, Subdepartment of Clinical Health Psychology, University College London, Torrington Place, London, UK; [email protected]

Sources of funding: NICE (National Institute for Clinical Excellence).

Evidence-Based Mental Health 7(4):p 115, November 2004.