The eIF2α kinase PKR modulates the hypoxic response by Stat3 -dependent transcriptional suppression of HIF-1α expression

¹McGill University/Lady Davis Institute for Medical Research, Medicine: Division of Experimental Medicine, Montreal, Canada, ²University of Thessaly, Laboratory of Physiology, School of Medicine, Larissa, Greece, ³Lady Davis Institute for Medical Research, McGill University, Montreal, Canada, ⁴Queen's University, Microbiology and Immunology and Pathology and Molecular Medicine, and Queen's University Cancer Institute, Kingston, Canada, ⁵University of Thessaly, Laboratory of Biochemistry, School of Medicine, and Institute of Biomedical Research and Technology, Larissa, Greece, ⁶McGill University/Lady Davis Institute for Medical Research, Department of Oncology, Faculty of Medicine, McGill University, Montreal, Canada