Immunogenicity and protective capacity of a CpG ODN adjuvanted alum adsorbed bivalent meningococcal outer membrane vesicle vaccine

Canavar Yildirim, Tugce
Ozsurekci, Yasemin
Yildirim, Muzaffer
Evcili, Irem
Yazar, Volkan
Aykac, Kubra
Guler, Ulku
Salih, Bekir
Gursel, Mayda
Gursel, Ihsan

Basic and Translational Research Program, Izmir Biomedicine and Genome Center, Izmir, Turkey
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Division of Pediatric Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Basic and Translational Research Program, Izmir Biomedicine and Genome Center, Izmir, Turkey
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Basic and Translational Research Program, Izmir Biomedicine and Genome Center, Izmir, Turkey
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Division of Pediatric Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Department of Chemistry, Hacettepe University, Ankara, Turkey
Department of Chemistry, Hacettepe University, Ankara, Turkey
Basic and Translational Research Program, Izmir Biomedicine and Genome Center, Izmir, Turkey
Basic and Translational Research Program, Izmir Biomedicine and Genome Center, Izmir, Turkey
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey

Correspondence to: I. Gursel; E-mail: [email protected]

Equally contributed to this work.

Received February 05, 2024

Accepted March 26, 2024

Revised June 12, 2024

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/pages/standard-publication-reuse-rights)

International Immunology 36(8):p 393-404, August 2024. | DOI: 10.1093/intimm/dxae016