Botulinum toxin A: a new approach to migraine prophylaxis?

Despite the availability of a number of agents for the acute treatment of migraine attacks, some patients do not achieve adequate relief of their symptoms or they experience adverse effects when taking these medications. For such individuals, prophylactic therapy may be a suitable approach to managing their migraines. At Headache World 2000 [London, UK; September 2000], the use of IM injections of botulinum toxin A ['Botox'] as prophylaxis for migraine was discussed in a symposium sponsored by Allergan Inc.