Development and Validation of Risk Matrices for Crohn’s Disease Outcomes in Patients Submitted to Early Therapeutic Interventions

^a Health Information and Decision Sciences Department, Faculty of Medicine of the University of Porto, Porto, Portugal

^b CINTESIS – Center for Health Technology and Services Research, Porto, Portugal

^c Gastroenterology Department, Hospital São João, Porto, Portugal

^d Gastroenterology Department, Faculty of Medicine, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal

^e Gastroenterology Department, Centro Hospitalar do Porto, Porto, Portugal

^f Gastroenterology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal

^g Gastroenterology Department, Centro Hospitalar Tondela e Viseu, Tondela e Viseu, Portugal

^h Gastroenterology Department, Hospital Garcia da Orta, Lisboa, Portugal

ⁱ Gastroenterology Department, Centro Hospitalar do Alto Ave, Guimarães, Portugal

^j Gastroenterology Department, Centro Hospitalar de Setúbal, Hospital São Bernardo, Setúbal, Portugal

^k Department of Biomedical Sciences and Medicine, University of Algarve, Faro, Portugal

^l Gastroenterology Department, Hospital de Faro, Faro, Portugal

^m Instituto Português de Oncologia Francisco Gentil, Lisboa, Portugal

ⁿ Gastroenterology Department, Centro Hospitalar Lisboa Oriental Portugal, Lisboa, Portugal

^o Gastroenterology Department, Hospital de Braga, Braga, Portugal

^p Gastroenterology Department, Portimão Unit, Centro Hospitalar do Algarve, Portimão, Portugal

^q Gastroenterology Department, Hospital Nélio Mendonça, Funchal, Portugal

^r Institute of Pharmacology and Therapeutics Faculty of Medicine of the University of Porto, Porto, Portugal

^s MedInUP – Center for Drug Discovery and Innovative Medicines, University of Porto, Porto, Portugal