Vogt-Koyanagi-Harada syndrome associated with renal failure: a case report

Zalts, Ronen
Hayek, Tony
Baruch, Ya'acov
Nakhoul, Farid
Miller, Benjamin

¹Department of Internal Medicine E, Rambam Medical Center and the Bruce Rappaport Faculty of Medicine, Technion, Haifa - Israel² Liver Diseases Unit, Rambam Medical Center and the Bruce Rappaport Faculty of Medicine, Technion, Haifa - Israel³ Departments of Nephrology, Rambam Medical Center and the Bruce Rappaport Faculty of Medicine, Technion, Haifa - Israel⁴ Department of Ophthalmology, Rambam Medical Center and the Bruce Rappaport Faculty of Medicine, Technion, Haifa - Israel

Address for correspondence: Ronen Zalts, M.D. Internal Medicine Department E Rambam Medical Center 31096 Haifa, Israel[email protected]

Received: July 26, 2005 Revised: August 26, 2005 Accepted: December 19, 2005

Journal of Nephrology 19(2):p 225-228, March-April 2006.

ABSTRACT:

Vogt-Koyanagi-Harada (VKH) syndrome is a rare entity characterized by depigmentation of the skin and eye lashes, chronic granulomatous iridocyclitis and exudative retinal detachment, as well as aseptic meningitis and encephalopathy. We describe a 22-year-old male intravenous drug addict, infected with hepatitis B and C virus, suffering from this syndrome, associated with progressive renal sclerosis, malignant hypertension, heart failure and chronic myeloproliferative disorder. The association with these various diseases is discussed and relevant cases are reviewed.