Immediate Placement and Provisionalization of Implants Into Sites With Periradicular Infection With and Without Antibiotics: An Exploratory Study

Givens, Edward Jr, DDS, MS
Bencharit, Sompop DDS, MS, PhD
Byrd, Warren C.
Phillips, Ceib MS, PhD
Hosseini, Bashir DDS
Tyndall, Donald DDS, MSPH, PhD

¹ Department of Prosthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC.
² Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC.
³ School of Dentistry, University of North Carolina, Chapel Hill, NC.
⁴ Department of Orthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC.
⁵ Department of Endodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC.
⁶ Department of Diagnostic Sciences, School of Dentistry, University of North Carolina, Chapel Hill, NC.

^* Corresponding author, e-mail: [email protected]

Journal of Oral Implantology 41(3):p 299-305, June 2015. | DOI: 10.1563/AAID-JOI-D-13-00002

This study explored the necessity of perioperative antibiotics on survival rates of implants immediately placed and provisionalized into sites with infection. Subjects were randomly assigned into antibiotic or placebo groups. Extraction, immediate placement, and provisionalization of an implant were performed. Eight subjects received placebo and five subjects received both a pre- and postoperative antibiotic regimen. One implant from each group failed. Perioperative antibiotic therapy may not be needed in selected immediate implant therapy.