Monomicrobial Rothia spp. Bloodstream Infections in Pediatric Patients and Literature Review

Green, Joshua D
Jaggi, Preeti
Gonzalez, Mark D
Patel, Pratik A

Emory University School of Medicine, Atlanta, GA, United States
Pediatric Infectious Disease at Children’s Healthcare of Atlanta, Emory University Department of Pediatrics, Atlanta, GA, United States
Department of Pathology, Children’s Healthcare of Atlanta, Atlanta, GA, United States
Pediatric Infectious Disease at Children’s Healthcare of Atlanta, Emory University Department of Pediatrics, Atlanta, GA, United States
Aflac Cancer & Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, GA, United States

Corresponding authors: Pratik A. Patel, Pediatric Infectious Disease at Children’s Healthcare of Atlanta, Emory University Department of Pediatrics, 2220 N Druid Hills Rd NE, Atlanta, GA 30329, United States ([email protected]) and Joshua D. Green, Emory University School of Medicine, 100 Woodruff Circle, Atlanta, GA 30322, United States ([email protected]).

Received April 09, 2025

Accepted August 08, 2025

Revised August 29, 2025

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/pages/standard-publication-reuse-rights)

Journal of the Pediatric Infectious Diseases Society 14(8), August 2025. | DOI: 10.1093/jpids/piaf074

Lay Summary

In the pediatric population, Rothia spp. bloodstream infections are more prevalent in cancer/hematopoietic cell transplant patients and frequently associated with prior broad-spectrum antibiotic use. These infections are commonly characterized by prolonged fever often without another identified infectious source.