Patient blood management during cardiac surgery

Do we have enough evidence for clinical practice?

Ranucci, Marco MD
Aronson, Solomon MD
Dietrich, Wulf MD, PhD
Dyke, Cornelius M. MD
Hofmann, Axel ME
Karkouti, Keyvan MD
Levi, Marcel MD, PhD
Murphy, Gavin J. MD, FRCS
Sellke, Frank W. MD
Shore-Lesserson, Linda MD
von Heymann, Christian MD

^aDepartment of Cardiothoracic-vascular Anesthesia and Intensive Care, IRCCS Policlinico S. Donato, Milan, Italy
^bDepartment of Anesthesiology, Duke University Medical Center, Durham, NC
^cWorking Group on Perioperative Hemostasis, Department of Anaesthesia, Ludwig Maximilian University Muenchen, Munich, Germany
^dSouthEast Texas Cardiovascular Surgery Associates, PA, Houston, Tex
^eCentre for Population Health Research, Curtin Health Innovation Research Institute (CHIRI), Curtin University, Perth, Western Australia
^fMedical Society for Blood Management, Laxenburg, Austria
^gDepartment of Anesthesia, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
^hDepartment of Vascular Medicine and Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
ⁱBristol Heart Institute, University of Bristol, Bristol Royal Infirmary, Bristol, United Kingdom
^jDivision of Cardiothoracic Surgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI
^kDepartment of Anesthesiology, Cardiothoracic Anesthesiology, Montefiore Medical Center, Bronx, NY
^lDepartment of Anaesthesiology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany

^∗Address for reprints: Marco Ranucci, MD, Department of Cardiothoracic-vascular Anesthesia and Intensive Care, IRCCS Policlinico S. Donato, Via Morandi 30, San Donato Milanese, Milan, 20097, Italy (E-mail: [email protected]).

Disclosures: The author group comprises the International Initiative on Haemostasis Management in Cardiac Surgery (IIHMCS). Members of the group were compensated for their presence at face-to-face meetings but not for the time invested in developing and reviewing the manuscript. Meeting organization and medical writing support for literature searches and manuscript preparation were provided by Physicians World Europe GmbH, Mannheim, Germany. Costs incurred for travel, hotel accommodation, meeting facilities, honoraria and preparation of the manuscript were supported by an unrestricted educational grant from Novo Nordisk Health Care AG, Zurich, Switzerland. The sponsor had no authorship or editorial control over the content of the meetings or any subsequent publication.

Drs Marco Ranucci and Solomon Aronson are co–first authors and cochairs of the International Initiative for Haemostasis Management in Cardiac Surgery (IIHMCS).

Received for publication January 24, 2011; revisions received February 9, 2011; accepted for publication April 8, 2011.

Journal of Thoracic & Cardiovascular Surgery 142(2):p 249e1-249e32, August 2011.