STORAGE OF TRANSFUSION PLATELET CONCENTRATES IS ASSOCIATED WITH COMPLEMENT ACTIVATION AND REDUCED ABILITY OF PLATELETS TO RESPOND TO PAR-1 AND TXA2R-ACTIVATION

¹Department of Chemistry and Biomedicine, Linnaeus University, Kalmar, Sweden

²Mayo Clinic, Rochester, MN

³Department of Clinical Chemistry and Transfusion Medicine, Region Kalmar County

⁴Department of Internal Medicine and Haematology, Semmelweis University, Budapest

⁵Hycult Biotechnology bevy, R&D department, Uden, The Netherlands

⁶Department of Immunology, Oslo University Hospital and University of Oslo, Oslo, Norway

⁷Centre of Molecular Inflammation Research, and Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

⁸Research Laboratory, Nordland Hospital, Bodo, Norway

⁹Department of Clinical Chemistry and Transfusion Medicine, Region Kalmar County, and Department of Biomedical

¹⁰Clinical Sciences, Division of Inflammation and Infection, Linköping University, Linköping, Sweden

¹¹Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden