IN RETROSPECT: Twenty-five years of thesex-determining gene

Marshall Graves, Jennifer A.

¹ Jennifer A. Marshall Graves is at the School of Life Science, La Trobe University, Melbourne, Victoria 3086, Australia, and at the Research School of Biology, Australian National University, Canberra.

Nature 528(7582):p 343-344, December 17, 2015. | DOI: 10.1038/528343a

The discovery that the geneSRYon the mammalian Y chromosome drives testis development marked a turning point in the decades-long quest to understand the genetic underpinnings and evolution of sex determination.