Lessons in Uncertainty and Humility — Clinical Trials Involving Hypertension

The Changing Face of Clinical Trials

Pfeffer, Marc A. M.D., Ph.D.
McMurray, John J.V. M.D.

From the Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston (M.A.P.); and the British Heart Failure Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom (J.J.V.M.).

Jeffrey M. Drazen, M.D., David P. Harrington, Ph.D., John J.V. McMurray, M.D., James H. Ware, Ph.D., Janet Woodcock, M.D., Editors

Address reprint requests to Dr. Pfeffer at the Cardiovascular Division, Brigham and Women's Hospital, 75 Francis St., Boston, MA 02115, or at [email protected].

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

New England Journal of Medicine 375(18):p 1756-1766, November 3, 2016. | DOI: 10.1056/NEJMra1510067