Professor and Chief of Obstetrics, University of Colorado Health Sciences Center, Denver Dr. Hobbins reports no financial relationship to this field of study.
Synopsis:Exposure to ACE inhibitors during the first trimester cannot be considered safe and should be avoided.
Source: Cooper WO, et al. Major congenital malformations after first-trimester exposure to ACE inhibitors. N Engl J Med. 2006;354:2443–2451.