Hyperreflective Ganglion Cell Layer Band in Gyrate Atrophy

Sen, Ahana DNB
Desai, Janhavi DO
Sharma, Survee MBBS
Thounaojam, Sanatombi MBBS
Kala, Urvashi DO, DNB
Majumdar, Bristi MBBS
Pradhan, Amrita MS, DNB
Chowdhury, Ruchira DO, DNB
Chattree, Surabhi MS
Saurabh, Kumar MS
Roy, Rupak MS

From the Department of Vitreo Retina Aditya Birla Sankara Nethralaya (AS, JD, SS, ST, UK, BM, AP, RC, SC, RR); and the Department of Vitreo Retina, Agarwals Eye Hospital (KS), Kolkata, West Bengal, India.

Disclosure: The authors have disclosed no potential conflicts of interest, financial or otherwise.

Address correspondence to Rupak Roy, MS, Aditya Birla Sankara Nethralaya, 147, Mukundapur, E.M.Bypass, Kolkata 700 099, West Bengal, India; email: [email protected].

Received January 09, 2024

Accepted May 24, 2024

Ophthalmic Surgery, Lasers and Imaging Retina 55(10):p 598-602, October 01, 2024. | DOI: 10.3928/23258160-20240528-04

We have described the hyperreflective ganglion cell layer band (HGCB) in a series of cases of gyrate atrophy. Clinical fundus examination and multimodal imaging which included optical coherence tomography (OCT) was done in all cases. Four patients (one male, three female) were studied. In all four cases, a hyperreflective band was noted in the ganglion cell layer. In three patients, the band was continuous, and in one patient, the band was patchy. To conclude, HGCB is a novel OCT sign in gyrate atrophy and can be valuable in prognostication of disease.

[Ophthalmic Surg Lasers Imaging Retina 2024;55:598–602.]