Childhood Methanol Ingestion Treated With Fomepizole and Hemodialysis

Brown, Mandy J. MD
Shannon, Michael W. MD, MPH
Woolf, Alan MD, MPH
Boyer, Edward W. MD, PhD

From the Children’s Hospital, Harvard Medical School, Boston, Massachusetts.

Received for publication Mar 5, 2001; accepted Jun 8, 2001.

Reprint requests to (E.W.B.) Children’s Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115. E-mail: [email protected]

Pediatrics 108(4):p e77, October 2001.

ABSTRACT.

Fomepizole (4-methylpyrazole; Antizol) is used increasingly in the treatment of methanol toxicity in adults. Little experience exists with this drug in the pediatric population, however. We present a case of methanol poisoning in a child in whom the use of fomepizole averted intravenous ethanol infusion and the attendant side effects of this therapy.