Evidence-Based Management Of Metabolic Emergencies In The Pediatric Emergency Department
- Ewing, Philip H. MD
- Wiebe, Robert A. MD
- Brancato, John C. MD
- Sharieff, Ghazala MD, FAAP, FACEP, FAAEM
A previously healthy 18-month-old girl presented to the emergency department with a 1-day history of poor feeding. On the morning of presentation, she was unarousable, so her parents called EMS. Paramedics arrived to find a somnolent child who was warm and well perfused, with a blood glucose level that was undetectable on a portable glucometer. She was given an infusion of glucose and transported to the ED, where she became somewhat more interactive. Blood and urine samples showed a normal blood sugar level and no ketonuria. The patient was continued on intravenous (IV) fluids containing dextrose and admitted to the hospital for observation. Her clinical course was unremarkable until that night, when she was weaned from IV fluids. At 4 am, her blood glucose level measured 47 mg/dL, and she was unarousable. As glucose was given, a more extensive laboratory panel was drawn, and her urine was collected a second time. The patient's diagnosis was made on the basis of these samples.