Epidemiology, Comorbidity, and Behavioral Genetics of Antisocial Personality Disorder and Psychopathy

Werner, Kimberly B. PhD
Few, Lauren R. PhD
Bucholz, Kathleen K. PhD

Kimberly B. Werner, PhD, is a Postdoctoral Scholar, George Warren Brown School of Social Work, Washington University. Lauren R. Few, PhD, is a Postdoctoral Scholar, Department of Psychiatry, Washington University School of Medicine. Kathleen K. Bucholz, PhD, is a Professor of Psychiatry, Department of Psychiatry, Washington University School of Medicine.

Address correspondence to Kimberly B. Werner, PhD, George Warren Brown School of Social Work, Washington University in St. Louis, 4560 Clayton Avenue, 1000 CID, St. Louis, MO 63110; email: [email protected].

Kathleen K. Bucholz discloses consulting fees from SetPoint Medical and Stryker as well as ownership interest in SetPoint Medical and Medtronic. The remaining authors have no relevant financial relationships to disclose.

Psychiatric Annals 45(4):p 195-199, April 01, 2015. | DOI: 10.3928/00485713-20150401-08

Psychopathy is theorized as a disorder of personality and affective deficits, and an Antisocial Personality Disorder (ASPD) diagnosis is primarily behaviorally based. Although ASPD and psychopathy are similar and are highly comorbid with each other, they are not synonymous. ASPD has been well studied in community samples with estimates of its lifetime prevalence ranging from 1% to 4% of the general population. In contrast, psychopathy is almost exclusively investigated within criminal populations so that its prevalence in the general population has been inferred by psychopathic traits rather than a disorder (1%). Differences in etiology and comorbidity with each other and other psychiatric disorders are also evident. This article briefly reviews the epidemiology, etiology, and comorbidity of ASPD and psychopathy, focusing predominately on research completed in community and clinical populations. The authors aim to highlight ASPD and psychopathy as related, but distinct disorders. [Psychiatr Ann. 2015;45(4):195–199.]