Cardiovascular Risk in Hashimoto’s Thyroiditis

Role of Thyroid Autoimmunity

Ranganadane, Rajarajeswari
S, Sumathi Saravanakumar
Raghavan, Srinivasan Abu
Shafiulla, Asmathulla
Subramanian, Girija
Selvi Nachimuthu, Maithili Karpaga

^1,4Department of Biochemistry, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India
^2,3Department of Biochemistry, Mahatma Gandhi Medical College and Research Institute, Puducherry, India
⁵Department of General Medicine, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India
⁶Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India

Corresponding Author: Sumathi Saravanakumar, Department of Biochemistry, Mahatma Gandhi Medical College and Research Institute, Puducherry, India, e-mail: [email protected]

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SBV Journal of Basic, Clinical and Applied Health Science 4(1):p 20-22, Jan-Mar 2021. | DOI: 10.5005/jp-journals-10082-03106

Hashimoto’s thyroiditis (HT) is the most common autoimmune thyroid disease synonymous with hypothyroidism. The link between hypothyroidism and the risk of cardiovascular diseases is of contemporary interest. Studies have indicated the prevalence of metabolic syndrome and endothelial dysfunction in HT patients. HT per se might possess a role in atherosclerosis. Association of HT with dyslipidemia and chronic inflammation leading to endothelial dysfunction has been documented. However, the role of thyroid autoimmunity in promoting cardiovascular diseases remains unclear. Further studies unraveling the causal relationship between HT and cardiovascular disease would provide greater insight into the management of atherogenic complications observed in HT patients.