1Neuroimmunology Unit, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden,2Neurodegeneration and Inflammation Genetics Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden,3Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm Sweden,4Molecular and Genetics Core, Diabetes Endocrinology Research Center, University of Washington, Seattle, WA, USA,5Salish Kootenai College, Pablo, MT, USA,6Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, Canada,7Diabetes and Cardiovascular Disease, Genetic Epidemiology, Department of Clinical Sciences, Skåne University Hospital, Lund, Sweden,8Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden,9Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden,10Department of Pediatrics, Ryhov County Hospital, Jönköping, Sweden,11Department of Medicine, Skåne University Hospital, Lund, Sweden,12Department of Pediatrics, Skåne University Hospital, Lund, Sweden,13Department of Pediatrics, The Queen Silvia Children's Hospital, Sahlgrenska/Ostra University Hospital, Göteborg, Sweden,14Department of Clinical Sciences, Skåne University Hospital, Malmö, Sweden,15Department of Pediatrics, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,16Division of Pediatrics and Diabetes Research Center, Department of Clinical and Experimental Medicine, Linkoping University, Linkoping, Sweden,17Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden,18Department of Medicine, University of Washington, Seattle, WA, USA,19Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden,20Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden, and21Department of Orthopaedics, Skåne University Hospital, Malmö, Sweden