1Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden. E-mail: [email protected], 2Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden. E-mail: [email protected], 3Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. E-mail: [email protected], 4Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden. E-mail: [email protected], 5Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden. E-mail: [email protected], 6Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland. E-mail: [email protected]. 7The Rockefeller University, Laboratory of Molecular Genetics and Immunology, New York, US. E-mail: [email protected], 8Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. E-mail: [email protected], 9Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden. E-mail: [email protected]