The State of Irreversible Electroporation in Interventional Oncology

Silk, Mikhail BS
Tahour, David MD
Srimathveeravalli, Govindarajan PhD
Solomon, Stephen B. MD
Thornton, Raymond H. RH, MD

¹ Section of Interventional Radiology, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York

Address for correspondence Raymond H. Thornton, RH, MD, Section of Interventional Radiology, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, [email protected]

Tumor Ablation; Guest Editor, Charles T. Burke, MD, FSIR

Seminars in Interventional Radiology 31(2):p 111-117, June 2014. | DOI: 10.1055/s-0034-1373785

Abstract

A new ablation modality, irreversible electroporation (IRE), has been of increasing interest in interventional radiology. Its nonthermal mechanism of action of killing tumor cells allows physicians the ability to ablate tumors in areas previously contraindicated for thermal ablation. This article reviews the current published clinical outcomes, imaging follow-up, and the current knowledge gaps in the procedure for patients treated with IRE.