Fine chemical synthesis with homogeneous palladium catalysts

examples, status and trends

Zapf, Alexander
Beller, Matthias

Institut für Organische Katalyseforschung an der Universität Rostock e.V. (IfOK), Buchbinderstr. 5-6, D-18055 Rostock, Germany

^*To whom correspondence should be addressed.

Topics in Catalysis 19(1):p 101-109, March 2002.

During the last decade several palladium-catalyzed reactions have been developed and optimized to a stage that enables application on an industrial scale. The importance of these reactions as novel key steps for fine chemical synthesis is shown. Examples include palladium-catalyzed Heck, Suzuki and Sonogashira coupling reactions, telomerization of 1,3-butadiene with nucleophiles, and carbonylation of aromatic and benzylic halides.