1Laboratory for Transplantation Immunology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland, 2Service of Immunology and Allergology, Department of Internal Medicine, University Hospital and Medical Faculty, Geneva, Switzerland
Address reprints request to Mårten K. J. Schneider, PhD, Laboratory for Transplantation Immunology, Department of Internal Medicine, University Hospital Zurich, Raemistrasse 100, C HOER 5, CH-8091 Zurich, Switzerland (E-mail: [email protected])
Abbreviations: Ab: antibody; CDC: complement-dependent cytotoxicity; CTL: cytotoxic T lymphocytes; EC: endothelial cells; Gal: galactose-α-1,3-galactose; GFP: green fluorescent protein; GT: α-1,3-galactosyltransferase; KO: knockout; NICC: neonatal porcine islet cell cluster; NK: natural killer; NOD-SCID: non-obese diabetic/severe combined immunodeficiency; PAEC: porcine aortic endothelial cells; PBMC: peripheral blood mononuclear cells; PCMV: porcine cytomegalovirus; PERV: porcine endogenous retrovirus; PLHV: porcine lymphotropic herpes virus; RBC: red blood cells; TF: tissue factor; TM: thrombomodulin; Treg: T-regulatory cell; WT: wild-type