Devoted to publishing original work on the pharmacodynamics and pharmacokinetics of drugs and nontherapeutic xenobiotics.
Its audience is scientists engaged in drug discovery and in identifying drug mechanisms of action. All areas of pharmacology are represented in the journal, including drug metabolism and kinetics. It is of particular value to those interested in anti-inflammatory drugs, cancer chemotherapy, neuropharmacology and cardiovascular pharmacology.
While particular emphasis is placed on reporting findings that relate to the actions and metabolism of drugs and toxic substances at the biochemical and molecular levels, submissions in the areas of behavioral and physiological pharmacology and toxicology are also encouraged if they describe studies directed at defining mechanisms of action.