Publication Year: 1999
Authors/Editor: Gomez, Manuel Rodriguez; Sampson, Julian R.; Whittemore, Vicky Holets
Publisher: Oxford University Press (OUP)
This new edition of a classic work includes a biological analysis of underlying genetic causes of this disease.
Tuberous Sclerosis is a genetic disease characterized by lesions of the skin and central nervous system, seizures, and sometimes sever mental retardation. Infants with this disease may appear overactive, autistic, or socially impaired. Because tuberous sclerosis involves abnormal cellular differentiation, aberrant neuronal migration, and excessive cell proliferation, this thoroughly revised edition will be of interest to a wide range of professionals involved in the study of biological mechanisms underlying many genetically determined neurological disorders.